DARU Journal of Pharmaceutical Sciences 2008. 16(Suppl. 1):54-57.

Topical application of Semelil (ANGIPARSTM) in treatment of pressure ulcers: A randomized clinical trial
Shamimi Nouri K, Karimian R, Nasli E, Kamali K, Chaman R, Farhadi M, Madani SH, Larijani B, Khorram Khorshid HR


Pressure ulcers are one of the major health care problems and results in a substantial amount of burden for both patients and health services. The aim of this study was to appraise effectiveness of topical Semelil (ANGIPARSTM), a naive herbal extract, in pressure ulcers As a randomized controlled clinical trial, 18 patients with pressure ulcers were recruited from Vali-e-Asr hospital, Medical Sciences/ University of Tehran, Iran. Nine patients received topical Semelil (ANGIPARSTM) during hospitalization and nine other patients received conventional treatment.

Baseline characteristics of the topical and control groups did not differ across demographic, clinical and functional measures. The mean surface areas of the ulcers were reduced 48.2 ± 85.3 cm2 (78.3%) and 2.8± 6.2 cm² (6.3%) in the treatment and control groups, respectively (p=0.000).

From the results of this study it may be concluded that the use of topical Semelil (ANGIPARSTM) with conventional treatment is more effective than those of only conventional treatment for patients with pressure ulcers.


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