DARU Journal of Pharmaceutical Sciences 2004. 12(3):87-93.

Bioactive lignans from the seeds of Centaurea macrocephala
Mohammad Shoeb, M. Mukhlesur Rahman, Lutfun Nahar, Abbas Delazar, Marcel Jaspars, Stephen M. Macmanus, Satyajit


The essential oil from flowering aerial parts of Nepeta depauperata Benth., an endemic Iranian plant, obtained by steam distillation was analyzed by GC/MS. The constituents were identified by their mass spectra and Kovats’ indices. Thirty-three compounds consisting 82.52% of the total components were identified from the oil obtained with a yield of 0.3%v/w. Among them, spathulenol (31.84%), beta caryophyllene (12.93%) and caryophyllene oxide (10.27%) were the major components of the oil.


Nepeta depauperata Benth, Essential oil composition, GC/MS, Spathulenol, Beta caryo-phyllene, Caryophyllene oxide,

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