Comparison of Indoie-aikafoids in Vinca major L, V. minor L. and Vinca herbacea L

Abstract

Eleven main alkaloids was observed in the leaf of Vinca major, of these, eight is determined: Ajmaline,Vindo[ine, Catharantine, Serpentine, Vincamine, Vincristine, Ajmalicine and Vinblastine. The known main alkaloids formed totally 41.5% and the unknown main alkaloids about 50.6% of the total alkaloid. The amount of the total alkaloid was 2.3 mg per gr of the fresh weight. Vincamine which was not present in V.rosea, was seen in V.major (8.2%).
Furthermore, Vindoline, Catharantine and Serpentine had a lesser amount in V.major, in comparison with V.rosea, respectively 3.7%, 18.1% and 6.3%. The mentioned eight known alkaloids and nine unknown alkaloids was observed in the leaf of V.minor. The known main alkaloids formed totally 37.1% and the unknown main alkaloids about 56.4% of the total alkaloids. The amount of the total alkaloid was 0.5 mg per gr of the fresh weight.All of alkaloids had a lesser amount in V.major, in comparison with alkaloids of similar to itself. Vincamine had the most percent (16.1%) and Vindoline (6.6%) and Serpentine (7.8%) were set after it.
It was observed, in addition to mentioned eight known alkaloids, eight unknown alkaloids in the leaf of V. herbacea. The known main alkaloids formed totaly 52.5% and the unknown main alkaloids about 41.5% of the total alkaloid.
The amount of the total alkaloid was 4.7 mg per gr of the fersh weight of the leaf. This amount is more than the amount which was observed in V.rosea (0.75), V.major (2,3), and V.minor (0.5).Vincamine had a high percent (39.8) and Serpentine a low percent (8.7). In short, V.herbacea is a good source for Vincamine and Serpentine, specially the last compound which easily is changed into Ajmalicine. V. rosea and V.major are a good source for Vindoline and Catharantine that can be used for providing Vinblastine and Vincristine.