DARU Journal of Pharmaceutical Sciences143IS THERE ANY RELATIONSHIP BETWEEN LITHIUM-INDUCED QT PROLONGATION AND PLASMA OR ERYTHROCYTE CONCENTRATION OF LITHIUM?136140SIMIN DASHTI-KHAVIDAKIHOSSEIN KHALILISEYED ALI AHMADI-ABHARIPADIDEH GHAELIMASOUD ESLAMIHASSAN FARSAMAHMAD-REZA DEHPOUR20151006This study was designed to find possible relationship between QTc prolongation and erythrocyte or plasma lithium concentrations. Fifty-six patients with bipolar disorder entered this case- control study. Subjects were between 17 to 63 years of age and were receiving lithium alone, or lithium plus haloperidol or lithium plus thioridazine. The exclusion criteria were past history of cardiovascular, hepatic, renal or metabolic disorders or using other medications known to cause rhythm disturbances. The case group included males with QTc 450ms and females with QTc470ms while the control group included males and females with QTchttps://daru.tums.ac.ir/index.php/daru/article/view/280https://daru.tums.ac.ir/index.php/daru/article/download/280/280