DARU Journal of Pharmaceutical Sciences111Simultaneous Spectrophotometric Determination of Mixtures of Food Colorants16Mad Reza OveisiMannan HajimahmoodiFatemeh Davami20151006Mixtures of food colorants, containing new coccine , ponceaue 6R and scarlet GN were simultaneously analyzed by spectrophotometry without previous chemical separation. Sixty mixtures of colorants with three-components were evaluated and the spectrograms were smoothed through the use of seven experimental points. The multivariate data consisted of normal, first- and second-derivative absorbance spectra (∆λ=5 nm) registered from 300-650 nm . The data obtained from experiments were processed by PLS method and the proposed method was applied satisfactorily for determination of these colorants in two commercial food products.https://daru.tums.ac.ir/index.php/daru/article/view/159https://daru.tums.ac.ir/index.php/daru/article/download/159/159