DARU Journal of Pharmaceutical Sciences103"Pharmacokinetic behavior of Amikacin in 31 Iranian critically ill septic patients "111119"Sabz Ghabaei AMMojtahed Zadeh MTajer Zadeh HAsasi NGanji MRMohagheghi AGholami KhHadavand N "20151006The pharmacokinetic behavior of amikacin and predictive performance of Sawchuk-Zaske dosing method, have been prospectively evaluated in 31 (16 male, 15 female) critically ill septic patients of mean (±SD) age of 58±23 years, mean ideal body weight of 59.6±6.4 kg, mean creatinine clearance of 52±21.5 ml/min, mean serum albumin of 3.1±0.5 mg/dl and median APACHE (acute physiology and chronic health evaluation) II score of 26 (with a range of 18 to 33). In this cross-sectional study, critically ill patients who met the Bone criteria for spesis but had stable creatinine clearance (serum creatinine changehttps://daru.tums.ac.ir/index.php/daru/article/view/150https://daru.tums.ac.ir/index.php/daru/article/download/150/150